Second Chance for Sophia & Friends: Reversing Rett Syndrome is a non-profit fundraising organization dedicated to raising money and awareness for Rett Syndrome.
Rett Syndrome is the most physically disabling of the Autism Spectrum Disorders. Its prevalence equals that of Cystic Fibrosis, Huntington’s and ALS, but is vastly under-funded by comparison.
Striking mainly little girls soon after they may have learned to walk and say a few words, the debilitating affliction causes symptoms from almost every neurological disorder including: loss of speech, motor control & functional hand use, disordered breathing and acute anxiety, impaired cardiac, circulatory & digestive functions, seizures and Parkinson’s tremors.
Mutations in MECP2 cause Rett Syndrome and have also been found in individuals diagnosed with Autism, learning disabilities, anxiety disorders, childhood onset schizophrenia and other neuropsychiatric disorders. Research on Rett Syndrome will have far-reaching implications for a myriad of these disorders.
This disorder *was* believed to be incurable. However, recently an unprecedented achievement arose: the reversal of Rett symptoms in a mouse model of the disorder by Dr. Adrian Bird.
Cutting edge clinical trials need funding to bring this study to our girls and reverse Rett Syndrome.
Donors' generous support has the potential to not only unlock the lives of Rett Syndrome sufferers, but also give substantive hope for new approaches to other disorders of the nervous system.